Perhaps people will be arguing about how only a very few people have access to genetic improvements.

Or perhaps, with future pandemics to come, and the rising MGTOW movement, only a select few people will be willing and/or able to make children, thus continuing to help the environment in an era of global warming.

Maybe these two things will combine, and relationships will become taboo and "too primal" because who would not want to just clone, enhance or cryobirth a new baby by making your sperm mate with each other?

Perhaps a "secular" form of Sharia law will become a thing in non-Muslim countries, and genders will be categorized based on the size of your dick. Anything under 5 inches and you are considered a woman and allowed to take female public transport.

Perhaps the Aliens will get in on the debate because Human's make the Aliens conscious about gender roles, and there will be Alien Red Pill and Feminists, and the relationships of their society also starts to break down?

Hey you know, I am a feminist but I just can't get over my attraction for what I continually culturally criticize yet also continually embody (ie this is the same as feminism is anticapitalist but my man needs to make at least 100k), them specifically masculine-traits. If these men want to masturbate with robots, then I will have no choice but to just genetically engineer my own super baby that will fuck the shit out of me and give me kids.