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Testosterone therapy may reduce prostate cancer risk due to testosterone deficiency at a young age via stabilizing serum testosterone levels

UnHope20

October 27, 2021

9 upvotes

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Post Information

Title	Testosterone therapy may reduce prostate cancer risk due to testosterone deficiency at a young age via stabilizing serum testosterone levels
Author	UnHope20
Upvotes	9
Comments	1
Date	October 27, 2021 10:16 AM UTC (4 years ago)
Subreddit	Posted in /r/Male_Studies
Original Link	https://old.reddit.com/r/Male_Studies/comments/qgte3z/testosterone_therapy_may_reduce_prostate_cancer/
Archive Link	https://theredarchive.com/r/Male_Studies/testosterone-therapy-may-reduce-prostate-cancer.1216152 https://theredarchive.com/post/1216152

Comments

[–]UnHope20[S] 1 point2 points3 points 4 years ago (0 children) | Copy Link

Objectives: To investigate whether testosterone replacement therapy (TRT) reduces prostate cancer (PCa) risk via stabilizing serum testosterone (T) levels beyond simply elevating serum T levels and whether TRT reduces PCa risk due to low serum T levels at a young age.

Results: We found the TRT group has more stable serum T levels (e.g. smaller drop-offs) during the follow-up period as compared to the non-TRT group, and the mean of MDRB is significantly higher in the untreated group (1.553 nmol/L VS 0.013 nmol/L; p-value < .001). TRT significantly reduces the risk of PCa associated with T deficiency at a young age (p-value = .00087).

Conclusions: TRT may reduce PCa risk via maintaining serum T levels within individual’s normal range; T surveillance may be needed for males who have low serum T levels at a young age to monitor abnormal variations of T levels and ensure timely treatment when necessary to reduce PCa risk.