I'm going out tonight alone for my second time. My first solo (night game) was last weekend, I've been into pickup for a few months so AA isn't a problem for me anymore (not really anyway) , but I was extremely nervous last weekend and it felt super awkward in my mind... until I actually got there and it felt EXACTLY like what I imagined it would... a sandbox that I could goto whenever I wanted to practice. Also, the BEST thing about it (or one of them) is that you can use the opener "I lost my friends..." to open shit loads of sets, then you can do routines and shit based off of that. It REALLY isn't harder than going with a friend(s), in fact its probably easier, have fun boys!

TL;DR: going out solo is no big deal, if anything its better. You can use an opener about your friends being lost and then game from there