I have a friend who had gotten into a relationship with a girl last September. All of us were in the same friend group and that is how they both met and eventually started dating. However, over time, he's realized how much of a maniac she really is and has a whole lot of mental issues and he's quite BPed but wants to get out of it somehow.

How would you suggest he break-up with her without her ruining his life and fucking up his reputation (within uni)? What should he know to stay as safe as possible from this situation?