I'm not talking about approaching multiple girls in the same night, but more like wether it's possible to try to approach a girl in a group (for example, at the university) and then approach another in case of rejection.

Rumours fly and it's very possible that if i approach a girl, the others will know and then if i try with another, they would probably view me as desperate, which is the worst. Is there a way to handle rejection in such a way that it doesn't hinder success with the other girls?

I'm asking this just because there are multiple girls i like in my class, but most of them are friends to a certain degree.