Gender Differences Are Encoded Differently in the Structure and Function of the Human Brain Revealed by Multimodal MRI

UnHope20 · 2023-02-15T01:13:49+00:00

Despite widely reported gender differences in both brain structure and brain function, very few studies have examined the relationship between the structural differences and the functional differences between genders. Here, different imaging measures including both structural [i.e., gray matter volume (GMV)] and functional [i.e., regional homogeneity (ReHo) and functional connectivity (FC)] measures were employed to detect the gender differences in the human brain based on univariate and multivariate approaches with a sample of 290 healthy adults (155 females). The univariate analyses revealed that gender differences were detected in both structural (i.e., GMV) and functional (ReHo or FC) imaging measures, mainly manifested as greater values in females than in males in regions of the frontal, parietal, occipital lobes and cerebellum.

Importantly, there was little overlap between the differences detected in GMV and those detected in ReHo and FC, and their differences between genders were not correlated with each other.

The multivariate pattern analyses revealed that each of these measures had discriminative power to successfully distinguish between genders (classification accuracy: 94.3%, 90.73%, and 83.89% for GMV, ReHo, and FC, respectively) and their combination further improved the classification performance (96.6%).

Our results suggest that gender differences are encoded in both brain structure and brain function, but in different manners. The finding of different and complementary information contained in structural and functional differences between genders highlights the complex relationship between brain structure and function, which may underlie the complex nature of gender differences in behavior.

nerdylernin · 2023-02-15T09:39:40+00:00

Is this cause or effect though? Are the changes due to differences in socialisation and interactions or a cause of them? It would be interesting (but probably unethical!) to see how gender differentiated neonates brains are vs. adult brains.

Title	Gender Differences Are Encoded Differently in the Structure and Function of the Human Brain Revealed by Multimodal MRI
Author	UnHope20
Upvotes	18
Comments	5
Date	February 15, 2023 1:11 AM UTC (3 years ago)
Subreddit	Posted in /r/Male_Studies
Original Link	https://old.reddit.com/r/Male_Studies/comments/112lozk/gender_differences_are_encoded_differently_in_the/
Archive Link	https://theredarchive.com/r/Male_Studies/gender-differences-are-encoded-differently-in-the.1215595 https://theredarchive.com/post/1215595

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