From my university level biology textbook on DNA mutations.
In humans, the average number of newly arising nucleotide-substitution mutations per genome in one generation is about 30, or about 60 per diploid zygote. Approximately 80% of the newly arising mutations in a zygote come from the father. The main reason is that, in a human male at age 30, the diploid germ cells have gone through about 400 cycles of DNA replication and cell division before meiosis takes place to form sperm cells, compared with about 30 cycles in females to form oocytes.Moreover, whereas the number of newly arising mutations from the mother remains approximately constant with the mother’s age, the number of newly arising mutations from the father increases with age. Sperm from men of age 40 contain about twice as many newly arising mutations as sperm from men of age 20.
Lots of jargon but in essence, sperm (diploid germ cells) go through many more cycles of DNA replications compared to woman’s egg cells. The possibility of mutations in DNA as a woman age is constant while this possibility continues to increase as men age like milk. Lmao as they say they don’t hit the wall 🤕
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