And same question about women: If they fuck a lot of guys in their youth then does that make it harder for them to have a meaningful monogamous relationship later on because they're addicted to the excitement/variety of sex?

Ideally it'd be awesome if you could have both abundant sexual variety early in youth and meaningful monogamy later on in life, but maybe you have to choose.

9 times out of 10 you can't have it both ways in life.