What does one say immediately preceding trying to kiss/hook up with a girl?

I've got everything else down. I'm good looking, I'm not shy, I know how to approach girls, I know how to flirt, I know how to get them interested in me, but holy shit for the life of me I don't know what to say once I've reeled the girl in and am ready to seal the deal. I searched extensively and was blown away by my failure to find an answer to this question. Does "Can I kiss you?" suffice? Should I just go for it without saying anything if the context seems appropriate? Could you provide me an example of what a generic conversation preceding a hook up consists of?

I'm aware this question seems stupid obvious, but I genuinely feel as if this is the only thing holding me back from dramatically improving my game.

Edit: To clarify, mostly concerned with a college party context.