I work at a ~5000+ person private company and I work with a lot of really cute, intelligent, fun girls. Are there different rules governing the workplace (I know I've alienated a couple of girls/groups already and that's never fun), or is this an area generally avoided by PUAs? These girls are going to have a basic work relationship with me already.

Full disclosure, this is really prompted by oneitis, but I thought I'd ask the question anyway.