Edit* When a comfort test comes with manipulation - Title error

I've been getting a lot of this lately. The why is something I'm working on, but that's not why I'm here.

What is the best RP approach to these situations? I've said before that I'm not against giving comfort, but I will not be manipulated into it. Wife, brother, mother, in-laws or the gas station attendant...doesn't matter. To me, it boils down to self respect.

I'm also aware I'm not an RP guru and I'm hoping, if there is any insight on these situations, that I will learn something new to get to a new stage. Or maybe refusing to give in is the best course of action for ourselves when this happens?

Shed some light on me, brothers.