After opening with a girl i find it sometimes difficult to transition into a natural conversation. After the opener i usually follow up with "how do you guys know each other?", give a light compliment, or introduce myself. Would it then be okay to move onto talking about where she is from, college etc.? Any tips on how it improve my conversation skills (especially on what to talk about in the first 5 minutes) would be greatly appreciated :)

EDIT: To specify, what i am looking for is content/topics to talk about in the first 5 minutes.