Have you ever heard about a problem that overwhemingly affects the opposite gender, meaning that >90% (or some very high percentage) of the people suffering from the problem are the opposite gender, and you don't immediately go "that's bullshit / it's actually not that bad to have such a problem / the problem is blown way out of proportion"? Instead they talk about how hard their life becomes as a result of that problem, and you feel genuine sympathy for them.

Do you have examples of such?