https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658214/

In this study of 42 individuals who presented to an ER alleging drink-spiking, none tested positive for known "date-rape" drugs like GHB or flunitrazepam(roofies).

Of the nine cases where illicit drugs were detected, only a mere three cases were depressants, where the possibility that it was a "date-rape" drug is even remotely plausible. And even then it may very well have been voluntarily ingested for recreational purposes.

https://sci-hub.se/10.1016/S1355-0306(05)71646-471646-4)

In this much larger sample of 180 individuals who presented to an ER alleging drink-spiking, again, none tested positive common date rape drugs like GHB or roofies.

At most, 11 cases tested positive for drugs with a sedative/disinhibitive effect that the authors hypothesize may be used for "date rape", but may very well have been voluntarily ingested:

"Specifically, benzodiazepines (e.g. temazepam), chlorpheniramine, opiates (e.g. codeine and dihydrocodeine), tramadol and zopiclone."

https://sci-hub.se/https://pubmed.ncbi.nlm.nih.gov/16054005/

In this even larger study involving over 1000 cases:

In 21 cases (2%), a sedative or disinhibiting drug was detected which had not been admitted and could therefore be an instance of deliberate spiking.

In all these studies, authors note that the complainants present to the ER shortly after the alleged incident, and these drugs remain detectable in urine for a long time, so it's highly unlikely that they missed anything.

I think what's going on is very obvious: women are incredibly paranoid and frequently suspect being "drugged" when in reality it's just the symptoms of their own voluntary alcohol/recreational drug consumption.

This is a vicious cycle, and leads to greater collective female paranoia and unwarranted hostility and suspicion towards men.